SECONDARY IMMUNITY RESPONSE OF MENCIT BALB / C (MUS MUSCULUS) EXPORTED BALI COW TESTISICULAR EXTRACT (BOS SONDAICUS)

Sri Novita Primawati

Abstract


Based on previous research by observing leukosit ploriferation of Balb / c mice given Balinese cow testical extract which showed significant result on observation to 72 hours after injection, while at 3 hours and 24 hours is not significant, it is suspected that the immunological response given to testicular extract a secondary immune response. This study aims to determine the ploriferation of Balb / c mice leukocytes exposed at some observation time, whether these include primary or secondary immune responses. Therefore it is necessary to do further research by adding exposure time of 1 day, 3 days, 5 days, and 7 days with only one exposure Con A (at 0 hour only). This study was designed with a complete randomized factorial design. The data obtained were analyzed by ANOVA analysis using F test. The results of this study showed that the influence of immunosuppression was highest on the third day (72 hours) and disappeared on the seventh day. This shows that the immunological response shown during observation of leukocyte proliferation of Balb / c mice is a secondary response.

Keywords


Testicular Extract, Balinese Cow (Bos sondaicus), Secondary Immune Response, Leucocyte Proliferation

Full Text:

PDF

References


Bone, J.F., 1982. Animal Anatomy and Physiologis, Seccond Edition, Respon Publishing Company, Amerika.

Dostal, J., et al, 1995, Immunosuppressive Effect Induced By Intraperitoneal and Rectal Administration of Boar Seminal Immunosuppressive Factor, Journal Biology Of Reproduction 52: 1209-1214.

Gandasoebrata, R., 1978. Penuntun Laboratorium Klinik, Dian Rakyat, Jakarta.

Hedger, M.P., and Meinhardt, A., 2003, Cytokines and The Immuno-Testicular Axis. J Reprod Immunol, 58:1-26.

Kresno, S.B., 2001. Imunologi: Diagnosis dan Prosedur Laboratorium, Edisi Ke-4, Gaya Baru, Jakarta.

Maddock, S., and Setchell, B.P., 1990. Recent Evidence for Immune Priviledge In The Testis, Journal.Reprod. Immun., 18:9-18.

Pollanen, P., Soder, O., Uksila, J., Nikula, H., Kaipia, A., Kangasniemi, M., Punnonen, J., Huhtamem, I., Parvinen, M., 1989. Testicular Immunosuppressive. Proceeding IVth Int. Cong. Androl. Monduzl Editor, Bologna, pp. 177 - 182.




DOI: https://doi.org/10.33394/j-ps.v1i2.1011

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2013 Sri Novita Primawati

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License
J-PS (Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram) p-ISSN (print) 2338-4530, e-ISSN (online) 2540-7899 is licensed under a Creative Commons Attribution 4.0 International License.

View My Stats