Identification of Medicinal Chemicals (BKO) Piroxicam in Jamu Pegal Linu Preparations in Makassar City

Hasnaeni Hasnaeni, Selpida Handayani, Velda Andina

Abstract


The aim of the research was to identify Piroxicam in herbal medicine for rheumatic pain circulating in Makassar. There are several traditional medicines that contain medicinal chemicals. Research has been conducted on the identification of medicinal chemicals (BKO) on several rheumatic herbs preparations in herbs shops in Makassar. The BKO which is often included in rheumatic herbs is the NSAID group, one of which is piroxicam. This inspection was conducted to know the presence of the chemical drug piroxicam contained within rheumatic herbs preparations and the samples used were 5 samples. The method used was a qualitative test using thin layer chromatography (TLC) consisting of a mobile phase mixed with n-hexane and acetone (7:3) and a stationary phase using Silica Gel GF254. The results of the TLC examination from 5 samples of herbal medicine added BKO piroxicam contained 3 samples including herbs A, B, and C because they had the same stain color at the same Rf value as the piroxicam. Some of the rheumatic herbs circulating in Makassar contain medicinal chemicals in the form of piroxicam.


Keywords


medical chemicals (BKO), piroxicam, rheumatic herbs, TLC

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Alyidrus, R., Ariastiwi, D. A., & Mardi, Y. 2019. Ekstrak etanol daun meniran (Phyllanthus niruri L.) terhadap mencit jantan (Mus musculus) yang diinduksi asam asetat sebagai analgetik. Media Farmasi, 15(1), 51-55.

Ayuni, N. P. S., & Sukarta, I. N. 2013. Isolasi dan Identifikasi Senyawa Alkaloid pada Biji Mahoni (Swietenia mahagoni Jacq). In Prosiding Seminar Nasional MIPA.

Bayani, F., Kurniasari, B. A., Hamdani, A. S., Yuliana, D., Wahyuni, I., Mujaddid, J., 2023., Identification of Secondary Metabolite Compounds from Melandean (Bridelian micrantha) Leaf Extract, Hydrogen : Jurnal Kependidikan Kimia, 11(6), 858-873.

Cahyaningtias, N., Amaniyah, L. R., & Widodo, H.S. 2022. Analisis Yuridis Terhadap Pengawasan Sediaan Obat yang tidak Memiliki Izin Edar pada Saat Pandemi Covid-19 di Indonesia. Jurnal Kolaboratif Sains, 5(8), 586–602.

Depkes RI, 2020. Farmakope Indonesia Edisi VI. Departemen Kesehatan RI

Fatimah, S., Rahayu, M., & Indari, D.F. 2017. Analysis of Antalgin in Jamu Pegal Linu Sold in Beringharjo Market, Yogyakarta. Journal of Health (JOH), 4(1), 29-34.

Fauziyah, B. 2012. Qualitative Analysis of Phenylalanine by Paper Chromatography and Thin Layer Chromatography (Initial Study of Phenylketonuria Disease Detection Method Development). Saintis (Journal of Integration of Science and Islam). 1(2), 10-18.

Gitawati, R., 2013. Analisis Adulterasi Jamu Pegal Linu yang Diperoleh Dari Pasar Jakarta dan Sekitarnya (Analysis of Adulterated Jamu Pegal Linu Obtained from the Market ini Jakarta). Buletin Penelitian Sistem Kesehatan, 16(3), 269-274.

Hamka, Z., Arief, R., & Azmin, R. A. P. 2022. Effect of Graded Maceration Method on Yield Value and Thin Layer Cramotography Profile (Klt) of Basil Leaf Extract (Ocimum basilicum L.). Journal of Health Yamasi Makassar. 6(1), 154-162.

Hadi, F. S., Pribadi, F., Saputri, A, D., Pratiwi, N. L. S. E., & Fadika, U. 2022. Menggagas Pengaruh NSAID Terhadap Keberhasilan Penyembuhan Dari Asam Urat (Gout) Dan Covid-19. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 12(4), 785–794.

Hendriati, L., Hamid, I. S., Widodo, T., Surya, R. H., Wahyudi, A. E., & Rasdianto, D. D. 2021. Analgesic Activity Of Transdermal Patch Ethanol Extract Piper Nigrum L Fructus With Some Enhancers On Mice. Jurnal Farmasi Sains dan Praktis, 7(1), 67-73.

Husna, F. & Mita, S.R. 2020. Identification of Medicinal Chemicals in Traditional Male Stamina Medicine by Thin Layer Chromatography Method. Farmaka, 18(2), 16-25.

Jayanti, Aprilia, H., & Lukmayani, Y. 2015. Analisis Kualitatif Bahan Kimia Obat (BKO) Glibenklamid dalam Sediaan Jamu Diabetes yang Beredar Dipasaran. Prosiding Farmasi, 649–653.

Khairiyah, N., Anam, S., & Khumaidi, A. 2016. Studi Etnofarmasi Tumbuhan Berkhasiat Obat Pada Suku Banggai Di Kabupaten Banggai Laut, Provinsi Sulawesi Tengah. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)(e-Journal), 2(1), 1–7.

Khasanah, K., Rusmalina, S., Safira, D., Setyorini, E. A., & Amanah, N. 2022. Penerapan Green Chemistry Pada Deteksi Kandungan Pewarna Universitas Muslim Indonesia 40 Berbahaya (Rhodamin B) Pada Produk Kosmetik yang Beredar Di Wilayah Pekalongan. Pena: Jurnal Ilmu Pengetahuan dan Teknologi, 36, 25-32.

Lani, D. N., Dewi, B. A., Anugerah, B., & Rosita, F. 2020. Identifikasi Bahan Kimia Obat Siproheptadin Hidroklorida Dalam Jamu Penambah Nafsu Makan Di Pasar Kecamatan Rengel Dengan Metode Kromatografi Lapis Tipis. Jurnal Ilmiah Kesehatan, 1(1).

Made, M. N. N., 2022. Identification of Paracetamol in Jamu Pegal Linu Obtained from Jamu Depots in Denpasar City Journal of Indonesian Pharmaceutical Research, 4(1) 74-88.

Manalu, S., & Putri Luhurningtyas, F. 2021. Identifikasi Paracetamol Pada Jamu Pegal Linu Yang Beredar Di Kawasan Ungaran Menggunakan Metode Kromatografi Lapis Tipis (KLT) Dan Spektrofotometri UV. Indonesian Journal of Pharmacy and Natural Product.

Masriani., Muharini, R., Wijayanti, D. K., Melania, P., Sari, M. L. W, 2023. Phytochemical Screening of Ethanol Extracts from Three Variants of Kratom Leaves (Mitragyna speciosa Korth.). Hydrogen: Jurnal Kependidikan Kimia, 11(2), 192-201.

Muhrodi, O., & Maesaroh, I. 2023. Identifikasi Bahan Kimia Obat Natrium Diklofenak Pada Jamu Pegal Linu Yang Dijual Di Kecamatan Garawangi. Jurnal Farmaku Kuningan), 8(1), 31-36.

Nasution, N. D. 2019. Identifikasi Bahan Kimia Obat Natrium Diklofenak Pada Jamu Pegal Linu Secara Kromatografi Lapis Tipis Yang Dijual di Jalan A. H. Nasution Medan Johor. Karya Tulis Ilmiah. Jurusan Farmasi: Poltekes Kemenkes Medan.

Nerdy, N., 2020. Penyuluhan Tentang Pemberian Obat Piroxicam Pada Pasien Yang Menderita Penyakit Rematik Pada Usia 50 Tahun Di Puskesmas Deli Tua. Jurnal Pengabdian Masyarakat Putri Hijau, 1(1), 44–48.

Ningrum, W. A., Wirasti, W., & Sugeng, P. 2018. Identifikasi Kandungan Bahan Kimia Obat (Paracetamol dan Prednison) dalam Kandungan Jamu Rematik GI dan MT di Pekalongan. In Prosiding University Research Colloquium (pp. 714-720).

Padanun, M. A. V., & Minarsih, T. 2021. Analysis of Diclofenac Sodium in Samples of Jamu Pegal Linu Sold in Semarang Regency by Uv-Vis Clt-Spectrophotometry. Journal of Holistics and Health Sciences, 3, 2150-2153.

Palupi, D. A., & Wardani, P.I. 2017. Tingkat Penggunaan Obat Anti Inflamasi Non Steroid (AINS) Di Apotek GS Kabupaten Kudus. Jurnal Keperawatan Dan Kesehatan Masyarakat Cendekia Utama, 2(5).

Parawansa, K.A., Masriani1., Sasri, R., Sapar, A., Erlina, Ersando. 2023. The Effect of Different Solvents on Total Tannin Content of Cengkodok (Melastoma malabathricum) Leaf Extracts, Hydrogen : Jurnal Kependidikan Kimia, 11(6), 821-834.

Pratiwi, R., Saputri, F.A. and Nuwarda, R.F., 2018. Tingkat pengetahuan dan penggunaan obat tradisional di masyarakat: studi pendahuluan pada masyarakat di Desa Hegarmanah, Jatinangor, Sumedang. Dharmakarya, 7(2), pp.97-100.

Rahmatullah, S., Slamet, S., & Fikri, A. 2018. Qualitative Analysis of the Content of Medicinal Chemicals (BKO) in Uric Acid Herbs Circulating in Pekalongan Regency. Proceeding of the URECOL, 566-575.

Rusmalina, S., Khasanah, K. and Nugroho, D.K., 2020. Deteksi asam mefenamat pada jamu pegel linu yang beredar di wilayah Pekalongan. Pharmacon: Jurnal Farmasi Indonesia, pp.51-60. Sari, N. P. D., & Haresmita, P. P. (2023). Analisis Kualitatif Bahan Kimia Obat dalam Jamu Pegal Linu di Wilayah Magelang. Jurnal Ilmu Farmasi dan Farmasi Klinik, 20(1), 53-59.

Sidoretno, W. M., & Rz, I. O. 2018. Education on the Dangers of Medicinal Chemicals Found in Traditional Medicines. In Journal of Community Service E-ISSN, 1(2).

Sarker, S. D., & Nahar, L. 2012. Natural Products isolation. Humana Press, 32.




DOI: https://doi.org/10.33394/hjkk.v12i1.10576

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