Tepung Labu Kuning (Cucurbita moschata), Tepung Porang (Amorphophallus muelleri Blume), dan Kombinasi Kedua Tepung sebagai Penurun Gula Darah dan Peningkat Motilitas Spermatozoa Mencit (Mus musculus)
Abstract
Keywords
Full Text:
Full PaperReferences
Aslam, H., Rafique, S., Mumal, S., Shah, A., Zainub, A., & Khokhar, A. (2021). Comparison of Glucose Lowering Ability of Pioglitazone and Glimepiride in Steptozotocin Induced Type 2 Diabetes Mellitus Male Mice Model. Pakistan Journal of Medical & Health Sciences, 15(6), 2156-2158. https://doi.org/10.53350/pjmhs211562156
Ataman, M. B., Dönmez, H. H., Dönmez, N., Sur, E., Bucak, M. N., & Çoyan, K. (2014). Theriogenology Protective Effect of Esterified Glucomannan on Aflatoxin-Induced Changes in Testicular Function, Sperm Quality, and Seminal Plasma Biochemistry in Rams. Theriogenology, 81(3), 373-380. https://doi.org/10.1016/j.theriogenology.2013.10.007
Condorelli, R. A., Vignera, S. L., Mongioì, L. M., Alamo, A., & Calogero, A. E. (2018). Diabetes Mellitus and Infertility: Different Pathophysiological Effects in Type 1 and Type 2 on Sperm Function. Frontiers in Endocrinology, 9(1), 1-9. https://doi.org/10.3389/fendo.2018.00268
Corona, G., Giorda, C. B., Cucinotta, D., Guida, P., & Nada, E. (2016). Sexual Dysfunction in Type 2 Diabetes at Diagnosis : Progression Over Time and Drug and Non-Drug Correlated Factors. PLoS ONE, 11(10), 1-14. https://doi.org/10.1371/journal.pone.0157915
Dar, A. H., Sofi, S. A., & Rafiq, S. (2017). Pumpkin the Functional and Therapeutic Ingredient: A Review. International Journal of Food Science and Nutrition, 2(1), 158-173.
Dra, L. A., Sellami, S., Rais, H., Aziz, F., Aghraz, A., Bekkouche, K., Markouk, M., & Larhsini, M. (2019). Antidiabetic Potential of Caralluma europaea against Alloxan-Induced Diabetes in Mice. Saudi Journal of Biological Sciences, 26(6), 1171-1178. https://doi.org/10.1016/j.sjbs.2018.05.028
Elakhdar, N., Bawab, R., & Borjac, J. (2020). Effect of Ceratonia Siliqua and Cucurbita Pepo Seeds Extracts on Spermatogenesis in Male Mice. BAU Joural - Healt and Wellbeing, 3(1), 1-12. https://doi.org/10.54729/2789-8288.1045
Evans, E. P. P., Scholten, J. T. M., Mzyk, A., Martin, C. R. S., Llumbet, A. E., Hamoh, T., Arts, E. G. J. M., Schirhagl, R., & Cantineau, A. E. P. (2021). Male Subfertility and Oxidative Stress. Redox Biology, 46(1), 1-17. https://doi.org/10.1016/j.redox.2021.102071
Fallah, A., Hasani, A. M., & Colagar, A. H. (2018). Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization. Journal of Reproduction & Infertility, 19(2), 69-81.
Fatchiyah, F., Nurmasari, D. A., Masruro, N., Rohmah, R. N., Triprisila, L. F., Mulyati., Yamada, T., & Ohta, T. (2019). Level of mRNA Insulin Gene and Blood Glucose STZ-Induced Diabetic Rat are Improved by Glucomannan of Amorphophallus muelleri Blume from East Java Forest Indonesia. Journal of Tropical Life Science, 9(2), 163-169. https://doi.org/10.11594/jtls.09.02.05
Fitri, M. T. A. (2021). Potensi Pemberian Tepung Labu Kuning (Cucurbita moschata) Tepung Porang (Amorphophallus muelleri Blume) dan Kombinasi Kedua Tepung terhadap Viabilitas Spermatozoa Mencit Putih (Mus musculus) yang Hiperglikemia. Skripsi. Universitas PGRI Adi Buana Surabaya.
Harchegani, A. B., Dahan, H., Tahmasbpour, E., Kaboutaraki, H. B., & Shahriary, A. (2018). Effects of Zinc Deficiency on Impaired Spermatogenesis and Male Infertility : The Role of Oxidative Stress, Inflammation, and Apoptosis. Human Fertility, 23(1), 5-16. https://doi.org/10.1080/14647273.2018.1494390
Iskandar. (2017). Pengaruh Pemberian Makanan Tambahan Modifikasi terhadap Status Gizi Balita. Jurnal AcTion : Aceh Nutrition Journal, 2(2), 120-125. https://doi.org/10.30867/action.v2i2.65
Kifle, Z. D., & Belayneh, Y. M. (2020). Antidiabetic and Anti-Hyperlipidemic Effects of the Crude Hydromethanol Extract of Hagenia abyssinica (Rosaceae) Leaves in Streptozotocin-Induced Diabetic Mice. Diabetes, Metabolic Syndrome and Obesity, 13(1), 4085-4094. https://doi.org/10.2147/DMSO.S279475
Kuhre, R. E., Albrechtsen, N. J. W., Larsen, O., Jepsen, S. L., Møller, E. B., Andersen, D. B., Deacon, C. F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, R., Hartmann, B., Rosenkilde, M. M., & Holst, J. J. (2018). Bile Acids are Important Direct and Indirect Regulators of the Secretion Of Appetite and Metabolism-Regulating Hormones from the Gut and Pancreas. Molecular Metabolism, 11(1), 84-95. https://doi.org/10.1016/j.molmet.2018.03.007
Kulczyński, B., Sidor, A., & Michałowska, A. G. (2020). Antioxidant Potential of Phytochemicals in Pumpkin Varieties Belonging to Cucurbita moschata and Cucurbita pepo species. CyTA : Journal of Food, 18(1), 472-484. https://doi.org/10.1080/19476337.2020.1778092
Kurniati, N. F., & Rosyadi, A. T. Y. (2022). The Effect Of Green Tea And Black Tea In Cheese Tea Drinks On Body Weight And Diabetes Mellitus Risk In Male Swiss Webster Mice. Acta Pharmaceutica Indonesia, 47(1), 43-47. https://doi.org/10.5614/api.v47i1.17043
Lotti, F., & Maggi, M. (2023). Effects of Diabetes Mellitus on Sperm Quality and Fertility Outcomes : Clinical Evidence. Andrology, 11(2), 399-416. https://doi.org/10.1111/andr.13342
Nasiri, K., Akbari, A., Nimrouzi, M., Ruyvaran, M., & Mohamadian, A. (2021). Safflower Seed Oil Improves Steroidogenesis and Spermatogenesis in Rats With Type II Diabetes Mellitus by Modulating the Genes Expression Involved in Steroidogenesis, Inflammation, and Oxidative Stress. Journal of Ethnopharmacology, 275(1), 1-20. https://doi.org/10.1016/j.jep.2021.114139
Natalia, E. D., Widjanarko, S. B., & Ningtyas, D. W. (2014). Uji Toksisitas Akut Tepung Glukomanan (Amorphophallus muelleri Blume) terhadap Nilai Kalium Tikus Wistar. Jurnal Pangan dan Agroindustri, 2(1), 132-136.
Petersmann, A., Nauck, M., Wieland, D. M., Kerner, W., Müller, U. A., Landgraf, R., Freckmann, G., & Heinemann, L. (2018). Definition, classification and diagnostics of diabetes mellitus. Experimental and Clinical Endocrinology & Diabetes, 126(7), 406-410. https://doi.org/10.1055/a-0584-6223
Prasetyaning, L., Purnamasari, R., & Lusiana, N. (2018). Efektivitas Mikronutrien Zinc dari Ekstrak Labu Kuning (Cucurbita moschata D) terhadap Perilaku Kawin Mencit (Mus musculus) Jantan. BIOTROPIC : The Journal of Tropical Biology, 2(1), 53-60. https://doi.org/10.29080/biotropic.2018.2.1.53-60
Pratama, R. Y., Pranitasari, N., & Purwaningsari, D. (2020). Pengaruh Ekstrak Daun Sirsak terhadap Gambaran Histopatologi Pankreas Rattus Norvegicus Jantan yang Diinduksi Aloksan. Hang Tuah Medical Journal, 17(2), 116-129.
Purnamasari, R., Lusiana, N., Widayanti, L. P., & Kumalasari, M. L. F. (2022). The Effectiveness of Zinc Micronutrients From Pumpkin (Cucurbita moschata D.) Extract on the Testosterone Levels of Mice (Mus musculus L.). Indian Journal of Forensic Medicine & Toxicology, 16(1), 986-993. https://doi.org/10.37506/ijfmt.v16i1.17623
Raja, M. A., Mondal, P., Venu, K., Thimmaraju, M. K., & Kiran, P. (2020). Food-Drug Interaction and Pharmacokinetic Study Between Fruit Extract of Capsicum frutescens L., and Glimepiride in Diabetic Rats. Clinical Phytoscience, 6(1), 1-13. https://doi.org/10.1186/s40816-020-00191-y
Saeedi, P., Petersohn, I., Salpea, P., Malanda, B., Karuranga, S., Unwin, N., Colagiuri, S., Guariguata, L., Motala, A. A., Ogurtsova, K., Shaw, J. E., Bright, D., & Williams, R. (2019). Global and regional Diabetes Prevalence Estimates for 2019 and Projections for 2030 and 2045 : Results from the International Diabetes Federation Diabetes Atlas, 9th Edition. Diabetes Research and Clinical Practice, 157(1), 1-10. https://doi.org/10.1016/j.diabres.2019.107843
Sarian, M. N., Ahmed, Q. U., So'ad, S. Z. M., Alhassan, A. M., Murugesu, S., Perumal, V., Mohamad, S. N. A. S., Khatib, A., & Latip, J. (2017). Antioxidant and Antidiabetic Effects of Flavonoids : A Structure-Activity Relationship Based Study. Hindawi : BioMed Research International (2017), 1-14. https://doi.org/10.1155/2017/8386065
Shadfar, S., Parakh, S., Jamali, M. S., & Atkin, J. D. (2023). Redox Dysregulation as a Driver for DNA Damage and its Relationship to Neurodegenerative Diseases. Translational Neurodegeneration, 12(1), 1-34. https://doi.org/10.1186/s40035-023-00350-4
Sharmin, R., Khan, M. R., Akhtar, M. A., Alim, A., Islam, M. A., Anisuzzaman, A. S. M., & Ahmed, M. (2013). Hypoglycemic and Hypolipidemic Effects of Cucumber, White Pumpkin, and Ridge Gourd in Alloxan Induced Diabetic Rats. Journal of Scientific Research, 5(1), 161-170. https://doi.org/10.3329/jsr.v5i1.10252
Srivastava, N., Sahu, P., & Banerjee, M. (2021). Nutraceutical Potential of Pumpkin (Cucurbita sp.) Powder, Seed, Extracts, and Oil on Diabetes; Mini Review. Journal of Endocrinology and Disorders, 5(1), 1-3. https://doi.org/10.31579/2640-1045/063
Susanti, N. (2014). Suplementasi Tepung Porang (Amorphophallus muelleri Blume) sebagai Nutraceutical dalam Manajemen Diabetes Mellitus Tipe 2. El-Hayah, 5(1), 9-16. https://doi.org/10.18860/elha.v5i1.3035
Suwannapong, A., Talubmook, C., & Promprom, W. (2023). Evaluation of Antidiabetic and Antioxidant Activities of Fruit Pulp Extracts of Cucurbita moschata Duchesne and Cucurbita maxima Duchesne. Hindawi : The Scientific World Journal (2019), 1-12. https://doi.org/10.1155/2023/1124606
Taye, G. M., Bule, M., Gadisa, D. A., Teka F., & Abula, T. (2020). In Vivo Antidiabetic Activity Evaluation of Aqueous and 80% Methanolic Extracts of Leaves of Thymus schimperi (Lamiaceae) in Alloxan-Induced Diabetic Mice. Diabetes, Metabolic Syndrome, and Obesity : Targets and Therapy, 13(1), 3205-3212. https://doi.org/10.2147/DMSO.S268689
Urli, T. I., Hariyanto T., & Dewi, N. (2017). Pengaruh Pemberian Tepung Porang (Amorphophallus muelleri Blume) terhadap Kadar HDL pada Tikus (Rattus novergicus) Strain Wistar DM Tipe 2. Nursing News : Jurnal Ilmiah Keperawatan, 2(2), 652-664. https://doi.org/10.33366/nn.v2i2.510
Wahyuni, D. (2017). Tepung Labu Kuning (Cucurbita mochata) Menurunkan Kadar Glukosa Darah Tikus Model Sindroma Metabolik. Aisyah : Jurnal Ilmu Kesehatan, 2(1), 11-16.
Widjanarko, S. B., Jamil, S. N. A., Ni'maturrahmah, E., & Putri, W. D. R. (2023). The Potential of Porang (Amorphophallus muelleri Blume) Flour and Porang Flour Formulation as an Anti-Diabetes Type-2 Agent. HAYATI : Journal of Biosciences, 30(5), 855-863. https://doi.org/10.4308/hjb.30.5.855-863
Zakiyah, A., Sukarjati., & Andriani, V. (2022). Sari Buah Stroberi (Fragaria vesca I.), Sari Buah Tomat (Solanum lycopersicum), dan Kombinasi antara Kedua Sari Buah untuk Meningkatkan Kualitas Spermatozoa Mencit yang Terpapar Asap Rokok Elektrik. Bioscientist : Jurnal Ilmiah Biologi, 10(1), 141-155. https://doi.org/10.33394/bioscientist.v10i1.4803
DOI: https://doi.org/10.33394/bioscientist.v11i2.8941
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Bioscientist : Jurnal Ilmiah Biologi is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
Editorial Address: Pemuda Street No. 59A, Catur Building Floor I, Mataram City, West Nusa Tenggara Province, Indonesia